The College's most significant contribution to the First World War came from its inventions and scientific advances made throughout the war. Official badges were issued to those engaged in war work. Just a few examples follow:
- J.C. Philip oversaw production of drugs in academic institutions
- Jocelyn Thorpe set up a drug production line in the Chemistry department
- Trench warfare under the control of Martha Annie Whiteley who worked on lachrymatory gases; experimental trenches were constructed
- H. Brereton Baker worked on analysis of poison gases used by Germany, absorbants for gasses and a device for venting carbon monoxide after firing weapons in a pill box development and detection
- Hilda Judd and Dorothy Haynes of Botany worked on cold storage for foods
- Entomology Department worked on insecticides
- Aeronautical training was undertaken by Mechanical Engineering Professor W.E. Dalby
- Alfred Fowler, Professor of Astrophysics, worked on optics
- The Metallurgy Bessemer labs worked on Ministry of munitions work
- Mining Geology undertook oil testing for air ministry
- The physics department was involved in x-ray research, fuels and engines
- The Botany team worked on food science including large scale field experiments on wheat, cold storage, plant pathology and tropical hygiene
- The Biochemistry department investigated adhesives for aircraft
- The Entomology department worked on insecticides
- Engineering - Dalby - Admiralty Board of Inventions alternatives to steam engines in warships, diesel engines for submarines munitions manufacture
- J.T. Irwin from Electrical Engineering developed a giant parabolic reflector at Dover used as an early aircraft detection device
- Morley Davis from Geology created a one millionth map of Europe
- Percy Boswell worked on glass sands with the Ministry of Munitions
- Alumni also contributed to the war effort:
- William Sansome Tucker (RCS 1898-1902) as Major Tucker, was Director of Acoustical Research, Air Defence Experimental Establishment, Biggin Hill. He worked on artillery sound ranging in WW1 and afterwards continued government research on sound, that eventually led to the massive parabolic concrete sound mirrors still standing on the south coast, that would hopefully have detected the approach of enemy bombers. Construction was halted around 1937 when Wimperis set up the Tizard Committee on Radar.
- William Watson (1868-1919), RCS 1887-1890 and later Professor of Physics. He became Lieutenant Colonel and Director of Central Laboratory of Western Front and died from exposure to poisonous gas from the gas shells he examined.